The structure and function of the glucagon-like peptide-1 receptor …
Glucagon-like peptide-1(7-36)amide (GLP-1) is a 30-residue peptide hormone released from intestinal L cells following nutrient consumption. It potentiates the glucose-induced secretion of insulin from pancreatic beta cells, increases insulin ...
Effects of GLP-1-(7-36)NH2, GLP-1-(7-37), and GLP-1- (9-36)NH2 …
Although no clear biological role for GLP-1- (9-36)NH (2) in humans has been identified, recent studies in animals suggest two potential effects: to antagonize the effects of intact GLP-1 and to promote glucose disappearance in peripheral tissues.
Glucagon-like peptide-1 - Wikipedia
The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage, which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37).
The metabolite GLP-1 (9–36) is neuroprotective and anti …
The current study evaluates the neurotrophic, neuroprotective, and anti-inflammatory properties of the glucagon-like peptide-1 (GLP-1) (7–36) metabolite, GLP-1 (9–36). Endogenous GLP-1 (9–36) is produced by the cleavage of GLP-1 (7–36) and has distinct properties from its parent peptide.
Effects of GLP-1-(7–36)NH2, GLP-1-(7–37), and GLP-1- (9–36…
Apr 1, 2003 · Although no clear biological role for GLP-1- (9–36)NH 2 in humans has been identified, recent studies in animals suggest two potential effects: to antagonize the effects of intact GLP-1 and to promote glucose disappearance in peripheral tissues.
Mechanisms of action and therapeutic applications of GLP-1 and …
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients.
The structure and function of the glucagon-like peptide-1 ... - PubMed
Glucagon-like peptide-1 (7-36)amide (GLP-1) is a 30-residue peptide hormone released from intestinal L cells following nutrient consumption. It potentiates the glucose-induced secretion of insulin from pancreatic beta cells, increases insulin expression, inhibits beta-cell apoptosis, promotes beta-ce …
GLP-1(7–36) protected against oxidative damage and neuronal …
Feb 19, 2024 · Glucagon-like peptide-1 (GLP-1) (7–36) amide, an endogenous active form of GLP-1, has been shown to modulate oxidative stress and neuronal cell survival in various neurological diseases.
Glucagon Like Peptide 1 [7-36] Amide - an overview
Glucagon-like peptide-1-(7-36) amide (GLP-1) is a human incretin hormone responsible for the release of insulin in response to food. Pre-clinical and human physiological studies have demonstrated cardioprotection from ischemia-reperfusion injury. It can reduce infarct size, ischemic left ventricular dysfunction, and myocardial stunning.
Glucagon Like Peptide 1 [7-36] Amide - an overview
Glucagon-like peptide-1 (7–36)amide (GLP-1) is a secreted peptide that acts as a key determinant of blood glucose homeostasis by virtue of its abilities to slow gastric emptying, to enhance pancreatic insulin secretion, and to suppress pancreatic glucagon secretion.