The discovery of the new function of ATR in mitophagy provides insights into the physiological function of a DNA damage response regulator in neuropathies and tissue declines, as well as the aging ...

Are there key genes involved in TKI resistance in ccRCC? What mechanisms are associated with this development? A research team, led by Professor Ben Liu from the Department of Urology at the First ...

A project led by scientists at the University of Dundee’s School of Life Sciences and School of Medicine has been selected for the 2025 SPARK NS Translational award, aimed at accelerating scientific d ...

WFS1 and CISD2 regulate IP3R activity through their interaction. In Wolfram syndrome, their dysfunction reduces cytosolic ...

A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

Mar. 31, 2025 — New research reveals that lower proportions of specific sleep stages are associated with reduced brain volume in regions vulnerable to the development of Alzheimer's disease over ...

Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...