San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury ...

Rookie running back Isaac Guerendo was carted off the field early in the 49ers’ season finale in Arizona against the ...

Rookie running back Isaac Guerendo was carted off the field early in the 49ers’ season finale in Arizona against the Cardinals with a leg injury.

San Francisco 49ers running back Isaac Guerendo exited early in the team’s Week 18 matchup vs. the Arizona Cardinals. What’s the latest on the Niners’ rookie running back? What Happened to Isaac ...

San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers' season finale versus the Arizona ...

The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8. They have started ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...

The San Francisco 49ers entered Sunday's season finale against the Arizona Cardinals with a depleted roster. Quarterback Josh Dobbs took the reins in place ...