LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ...

When a child develops a brain tumor, early diagnosis is essential. Alan Cohen, M.D., director of pediatric neurosurgery at Johns Hopkins Children’s Center, shares the most common signs and symptoms ...

The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings, blocking the body’s immune defenses and creating a sort of haven ...

Researchers from Iwate Medical University and Tohoku University have revealed that it is possible to predict cancer relapse and treatment response by measuring circulating tumor DNA (ctDNA), in ...

According to her mom, Penny was diagnosed with Wilms tumor, which is cancer in the kidneys, last April. The Children's Hospital says 75% of cases occur in kids below the age of 5. Penny's mom says ...

We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy. Emerging strategies, such as logic-gated and dual-targeting ...

The main goal of surgery is to remove the entire Wilms tumor in one piece, if possible. This is important because Wilms tumors tend to be fragile. Cutting into them makes it more likely that some ...