Cutaneous melanoma, the most aggressive form of skin cancer, is characterized by its accumulation of a large number of ...

However, this therapy can also lead to severe, albeit treatable, side effects, such as cytokine release syndrome (CRS), immune ... tumor or effector cells: BM was flushed out of the femur and tibia of ...

Tumor lysis syndrome can occur when a patient’s body is not able to clear away waste released by dead cancer cells quickly enough after treatment for chronic lymphocyctic leukemia (CLL). Certain ...

School of Life Science and Technology, Shandong Second Medical University, Weifang 261053, Shandong, China ...

like glioblastoma), the presence of tumor-infiltrating neutrophils is the key factor that has prevented these therapies from working. Neutrophils are a type of white blood cell that the immune ...

We previously showed with a bilateral-tumor mouse model of TNBC that cryoablation of the primary tumor leads to increased infiltration ... blood cell lysis buffer (STEMCELL Technologies, Vancouver, ...

This failure often results from tumor evolution, both genotypic and phenotypic, away from sensitive cell states. Here, we propose a mathematical framework for studying the dynamics of adaptive immune ...