Laiho holds patents on RNA polymerase 1 inhibitors, which are managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.

In addition to its newly launched CleanScribe RNA Polymerase, TriLink offers mRNA capping analogs (including the award-winning CleanCap® M6), mRNA raw materials (nucleotides and other IVT enzymes ...

Simultaneous detection of tumor-derived mutations in DNA and RNA extracted from a single circulating tumor cell based on droplet digital polymerase chain reaction. Authors: Jaesung Choi, Sehwan Park, ...

DNA polymerase synthesizes double-stranded DNA molecules from unwound DNA strands during replication. Even though the end products of replication and transcription are different, they both work on DNA ...

The sigma H (σ Η) and sigma E (σ E) subunits of Corynebacterium glutamicum RNA polymerase belong to Group 4 of sigma factors, also called extracytoplasmic function (ECF) sigma factors. Genes of the C.

Applied DNA Sciences, Inc. (NASDAQ:APDN) ("Applied DNA" or the "Company"), a leader in PCR-based DNA technologies, today announced that it has acquired Spindle Biotech Inc. ("Spindle"), an early ...

Primordial Genetics, Inc., a synthetic biology company, announced the launch of its proprietary RNA polymerases to advance safe, viable mRNA-based vaccines and therapeutics. SAN DIEGO, Feb. 22, 2023 ...

This allows them to be inserted into the nascent RNA. Remdesivir (RDV) was developed to fight the Ebola virus back in 2014 but was repurposed against the current coronavirus disease 2019 (COVID-19).

Several COVID-19 RNA vaccines currently in clinical trials are exploring self-amplifying RNA technologies. mRNA vaccines beyond COVID-19 It is an exciting time for mRNA technologies.

DNA polymerase synthesizes double-stranded DNA molecules from unwound DNA strands during replication. Even though the end products of replication and transcription are different, they both work on DNA ...

Scientists at the University of Turku, Finland, and Penn State University, have figured out how cells tell apart the highly similar building blocks that go into making RNA and DNA polymer chains.

Self-amplifying RNA vaccines are derived from the genome backbone of an alphavirus in which the genes encoding the viral RNA replication machinery are intact but those encoding viral structural ...