By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology ...

The researchers found that using a drug to inhibit RNA Polymerase 1 (Pol 1) - the enzyme responsible for human ribosomal RNA (rRNA) transcription - triggered a unique stress response that rewires ...

SAN DIEGO--(BUSINESS WIRE)--TriLink BioTechnologies and Alphazyme, both part of Maravai LifeSciences, have collaborated to launch CleanScribe™ RNA Polymerase, a novel enzyme that reduces double ...

DNA polymerase was isolated in 1956; RNA polymerase, in 1959. Wave Life Sciences, a clinical-stage RNA medicines company, develops A-to-I RNA base editing oligonucleotides (“AIMers”).

Scientists have created an artificial RNA system that can copy itself using simple building blocks and temperature changes.

Using the RNA origami technique, they succeeded in producing nanotubes that fold into cytoskeleton-like structures. ... To implement the blueprint it contains, RNA polymerase is used.

The RNA polymerase's copying accuracy must exceed a critical threshold to maintain heritable information over multiple generations, ...

A breakthrough assay is advancing how researchers observe gene expression in real time. Named QRIVTA (quantitative real-time ...

A significant percentage of patients with SSc first present with non-RP symptoms — most commonly puffy fingers/hands — and are associated with more severe disease.