Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to be the key hormones that regulate lipid metabolism in the liver.

Fatty liver disease is a growing global health concern. Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to regulate lipid metabolism in the liver. However ...

Proglucagon-derived peptides are involved in a wide variety of both peripheral as well as central functions, such as glucose homeostasis, gastric emptying, insulin secretion and the regulation of ...

PCSK1: Encodes for enzymes that cleave Proglucagon into active GLP-1. GLP1R: Facilitates the creation of receptors that GLP-1 binds to, enabling its biological activity.

1) What impact do proglucagon and GIP gene peptide products have on pancreatic beta-cell function? We will assess secretory and functional effects of all peptide products on pancreatic alpha- and beta ...

As a counter to insulin, glucagon plays a vital role in diabetes, maintaining blood sugar levels and offering therapeutic potential for hypoglycemia.

Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to be the key hormones that regulate lipid metabolism in the liver.

These L cells make GLP-1 by the differential processing of proglucagon, a gene expressed in these cells.

Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to be the key hormones that regulate lipid metabolism in the liver.