Massive wildfires roaring through the Los Angeles area left neighborhoods in ruins Wednesday, killing at least five people and threatening landmarks made famous by Hollywood as desperate residents escaped through flames that spread out of control with help from hurricane-force winds.

At least two people were killed and tens of thousands were forced to evacuate as multiple wildfires devastated the Los Angeles area and stretched the region’s firefighting resources to its limits. A wind-fueled fire has raced through the affluent Pacific Palisades neighborhood and others sparked and quickly spread around Los Angeles County.