Objective: Newborns are highly susceptible to bacterial sepsis. Mannan-binding lectin (MBL), M-, L- and H-ficolin recognize microorganisms and activate the complement system via MBL-associated ...
In recent years, the complement system has been implicated in the pathophysiology and progression of many disorders, notably modulating inflammation and causing endothelial and organ damage 1.
About Zaltenibart (OMS906) Zaltenibart is an investigational human monoclonal antibody targeting mannan-binding lectin ... activator of the complement system’s alternative pathway.