Brown (ankle) is active for Sunday's matchup against the Cardinals, Lindsey Pallares of the 49ers ' official site reports.

Brown (ankle) is listed as questionable ahead of Sunday's matchup against the Cardinals, Bo Brack of GoPHNX.com reports. Brown appeared to be trending toward not playing in Sunday's divisional contest ...

Even though Brown and the San Francisco 49ers came up short in overtime against the Kansas City Chiefs, the way he represented Trenton on the grandest stage makes him our Trentonian SportsPerson ...

The 49ers are riding a tow game losing streak into Week 17. They are poised to increase it to three in their matchup with the Lions. Here are three reasons why the 49ers will lose to the Lions.

While the 49ers are more susceptible on the ground than through the air, Johnson’s playcalling tends to set St. Brown up to pay off on scoring drives. And it only helps that Jared Goff is ...

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

SANTA CLARA — The 49ers are set to head into their "Monday Night Football" contest with the Detroit Lions a little worse for the wear, especially at offensive line. Trent Williams (ankle ...

Charvarius Ward will join the list of 49ers missing Monday night’s game against the Lions at Levi’s Stadium after the team ruled him out Sunday afternoon. The veteran cornerback and his ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC ...

The Detroit Lions and San Francisco 49ers have released their final injury reports of the week ahead of their Monday night showdown in Week 17 and there are a total of six players ruled out and ...

On Monday at 8:15 p.m. ET, two of the top offensive players in the NFL will be featured when Jahmyr Gibbs and the Detroit Lions visit George Kittle and the San Francisco 49ers. The Lions sport the ...

There doesn't seem to be any question about quarterback Brock Purdy's future with the San Francisco 49ers. All indicators are the team is happy with his development and that his contract extension ...