Israel’s massive airstrike attack left Iran’s military leadership in crisis as it killed several senior Iranian commanders — including the head of its Revolutionary Guard.

Iran struck buildings in the heart of Israel, killing at least 10. Israeli strikes expanded to energy facilities, natural gas installations and government buildings.

Smoke and missiles have lit up the skies in Israel and Iran in a fierce standoff triggered by fears over Tehran’s expanding nuclear program. Since June 13, hundreds of military strikes have been exchanged as the two nations remain locked in a conflict that shows no signs of abating.

Israel’s military headquarters were struck after Iran’s Islamic Republic unleashed a barrage of missiles on central Tel Aviv late Friday night, causing “significant damage” to the Jewish state’s equivalent of the Pentagon.

Surveillance video shows the moment an Iranian missile struck a residential building in Petah Tikva, Israel. At least three people were killed in the strike, according to police, bringing the death toll in Israel to 24 since Iran launched its retaliatory strikes.