Neuroscience News4d
Mapping IL-1’s Role in Mood, Memory, and Sensory Circuits
A comprehensive study mapped neuronal IL-1R1 (nIL-1R1) expression in the mouse brain, highlighting its role in sensory ...
AZoLifeSciences on MSN1d
Mapping of Neuronal IL-1R1 Expression in the Mouse Brain Sheds Light on Mood and Memory
In disease, high levels of IL-1 in the brain are linked to neuroinflammation, which can disrupt the body's stress response, ...
Science Daily3d
'Ding-dong:' A study finds specific neurons with an immune doorbell
Neuroscientists have identified that the receptor IL-1R1 plays a critical role in enabling neurons to directly communicate with the immune system. The new study provides the most detailed mapping of ...
Armed robbery in Revesby4d
Research Finds Neurons With Immune Doorbell Function
Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states. In disease, high ...
BioWorld6d
Kymera Therapeutics describes IRAK-4 degraders
Kymera Therapeutics Inc. has patented new proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase-binding moiety coupled to an interleukin-1 receptor-associated kinase 1 ...