Both dietary and endogenous reactive carbonyl species, such as methylglyoxal (MGO) and glyoxal (GO), react with proteins to generate advanced glycation end products (AGEs), which contribute to ...
In the in vitro glycation assay, RuDiOBn inhibited the formation of advanced glycation end products in collagen via the glyoxal pathway, with an IC 50 (μg/mL) equal to 2.45 ± 0.47. In the cytotoxicity ...