We report the efficacy of a new peptide with agonism at the glucagon and GLP-1 receptors that has potent, sustained satiation-inducing and lipolytic effects. Selective chemical modification to ...

The hormone glucagon, secreted by the pancreas, ... "These results provide new insights into glucagon biology and suggest that mitochondrial calcium transport, mediated by INSP3R1, ...

However, when obese mice without INSP3R1 were chronically treated with glucagon, the hormone had no effect. “These results provide new insights into glucagon biology and suggest that mitochondrial ...

Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwestern Medical Center researchers ...

The 2024 Lasker–DeBakey Clinical Medical Research Award recognizes Drs. Habener, Mojsov, and Knudsen, who developed GLP-1 medicines that have revolutionized the treatment of obesity.

Glucagon can also play a role in how amino acids (compounds that help make up muscles and tissue in your body) make glucose. And it can break down triglycerides, or fat your body stores, into fuel.

The advantages of glucagon-like peptide-1 (GLP-1) medicines beyond glycemic and weight control. Skip to content. ... Discover how 3D biology, automation, and AI are revolutionizing drug discovery, ...

'Glucagon resistance is an entirely new biological concept that we will include in the future teaching of medical students, just as we do today with insulin resistance', says Nicolai J. Wewer ...

As for intranasal glucagon (Baqsimi), which was first FDA approved in July 2019, out-of-pocket costs were lower than unmixed glucagon for commercially insured patients. Median costs were $10.89 in ...