BioWorld3d
ICB treatment induces colitis-related indicators in DSS drinking mouse model
Researchers from Chinese Academy of Sciences detailed the creation of a new dextran sulfate sodium (DSS)-based mouse model of ...
eLife17d
A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient
The study provides convincing evidence for variable regeneration efficiency among planarian species that will be of interest to developmental biologists interested in regeneration. However, some of ...
SciELO22d
Coptisine ameliorates colitis in mice by modulating cPLA2/TRPM8/CGRP-1 signaling pathways and strengthening intestinal barrier function
Dextran sodium sulfate (DSS) (36-50 kDa, Catalog Number: 160110) was sourced from MP Biomedicals (Canada). E-cadherin antibody (Catalogue Number: HX14050) and occludin antibody (Catalogue Number: ...
gut.bmj12d
NAD metabolism fuels human and mouse intestinal inflammation
Design We investigated the impact of NAMPT inhibition by the small-molecule inhibitor FK866 in the dextran sulfate sodium (DSS) model of colitis and the azoxymethane/DSS model of colitis-associated ...
gut.bmj26d
Protective effects of Fc-fused PD-L1 on two different animal models of colitis
In this study, we investigated the effects of PD-L1-Fc treatment on intestinal inflammation using two murine models of inflammatory colitis induced by dextran sulfate sodium (DSS) and T-cell transfer.
EMBO Press5d
PARP7 as a new target for activating anti-tumor immunity in cancer
PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...
Sky18d
North Sea crash: Solong ship unlikely to stay afloat but wasn't carrying sodium cyanide, owners say
The owners of a container ship which crashed into another vessel in the North Sea on Monday have denied reports it had hazardous sodium cyanide on board. US tanker Stena Immaculate was anchored ...