With over 350 million adults worldwide expected to have metabolic dysfunction-associated steatohepatitis (MASH) by 2050,1 half with stage 2 or 3 liver fibrosis, there remains an unmet need for ...

An estimated 2·1 billion adults worldwide are affected by overweight and obesity, a figure projected to reach 3·8 billion by ...

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“I just want to be normal.” I've lost count of the number of times I've heard this phrase in my therapy room and, as a client in therapy, said it myself. In my previous career as a writer, I spent a ...

When approached for a quote about Jeffrey D Rothstein, Professor of Neurology and Neuroscience and Director of the Brain Science Institute at Johns Hopkins School of Medicine (Baltimore MD, USA), his ...

WHO has recognised mental health and, more recently, brain health as public health priorities.1 This momentum was further advanced at the National, Regional and International Plans for Brain and ...

More than 82 million people could be living with dementia by 2030,1 the majority in low-income and middle-income countries ...

Therapeutic advances have altered the neurodegenerative trajectory and improved clinical outcomes for individuals with spinal muscular atrophy. Current therapies increase concentrations of survival ...

Consciousness has many aspects, from wakefulness to complex cognitive feats, but sentience—ie, the capacity for feeling—is paradoxically simpler yet the most difficult aspect of consciousness to ...

Medicine has traditionally relied on a pathophysiology-to-phenotype paradigm, whereby specific pathological processes are linked to signs and symptoms. This paradigm maintains that complex systems are ...

Robert Eggers’ meticulous gothic interpretation of Nosferatu is a remake of the 1922 film directed by F W Murnau and based on ...

An Editorial in The Lancet Neurology emphasised that rigorous prospective studies are essential to develop safe and ethical artificial intelligence (AI) tools for brain health.1 Yet, what usually ...