Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

Iridium (Ir) catalysts are essential for the acidic oxygen evolution reaction (OER) in proton-exchange membrane water electrolyzers (PEMWEs), but their high cost, scarcity, and geographical ...

Polymer microneedles (MNs) attract considerable attention due to their sound biocompatibility and low manufacturing cost. In this study, we prepared polypropylene (PP) MNs utilizing ultrasonic ...

Fluorescence imaging in the shortwave infrared (SWIR) window enables deeper tissue and higher-contrast visualization of pathological events compared to that in the conventional near-infrared (NIR) ...

Frequency upconversion provides a feasible strategy for switching the resonant wavelength of lasing modes. However, this nonlinear process requires extremely high optical properties for the medium.

Major challenges remain to precisely detect low-abundance proteins rapidly and cost-effectively from diverse biofluids. Here, we present a gold nanoparticle (AuNP)-supported, rapid electronic ...

Proteolysis-targeting chimeras (PROTACs) are an emerging class of therapeutic agents for anticancer treatments by degrading intracellular proteins via the ubiquitin-proteasome system. However, ...

Correction to “Stealth Polydopamine-Based Nanoparticles with Red Blood Cell Membrane for the Chemo-Photothermal Therapy of Cancer” ...

Water structuring critically influences reactivity in aqueous electrocatalysis, yet the roles of interfacial water networks in electrode kinetics remain poorly defined. Here, we use the hydrogen ...

A facile asymmetric synthesis of α,α-disubstituted amino acid derivatives was achieved via gold redox catalysis. The in situ formed aryl gold(III) served as the key intermediate toward alkyne ...

The asymmetric hydrogenation of substituted benzenes with oxazoline imino (pyridine) (OIP) molybdenum precatalysts is described. A comparison of the hydrogenation activities between alkylbenzenes and ...

Antimicrobial peptides (AMPs) are promising alternatives to traditional antibiotics. This study uses alchemical free energy simulations to design ultrashort, cationic, broad-spectrum membrane-active ...