The New York Yankees (51-41) host the Seattle Mariners (48-44) Thursday in the final game of their series at Yankee Stadium. First pitch is scheduled for 7:05 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Mariners vs. Yankees odds and make our expert MLB picks and predictions for the best bets.

With another series loss at the hands of the Yankees, the Mariners have now lost of split 18 of the last 21 series against the organization since 2014.

The New York Yankees will take on the Seattle Mariners in an MLB matchup on Thursday. This prediction features our best bet of the game.

At one point in the top of the eighth, the Yankees' odds of winning the game dipped to 1.3%. At that juncture, the Mariners led 5-0, and All-Star right-hander Bryan Woo was working on what would have been the first no-hitter of the 2025 Major League Baseball season.

Anthony Volpe scored the winning run with an acrobatic slide on Aaron Judge’s shallow sacrifice fly in the 10th inning, and the New York Yankees rallied past Seattle 6-5 after Mariners pitcher Bryan Woo took a no-hitter into the eighth.

Anthony Volpe scored the tiebreaking run on a bases-loaded sacrifice fly by Aaron Judge in the 10th inning and the host New York Yankees extended their winning streak by rallying for a 6-5 victory over the Seattle Mariners after being held hitless by Bryan Woo through seven innings on Thursday night.