The University of Hong Kong has patented RNA polymerase β subunit/RNA polymerase sigma factor RpoD (bacterial) interaction inhibitors reported to be useful for the treatment of gram-positive bacterial ...
Bacterial RNA polymerase (RNAP) has emerged as a crucial target for antibiotic development due to its essential role in transcription. RNAP is a molecular motor, and its function relies heavily on the ...
On Monday, Sigma introduced its latest full-frame mirrorless digital camera—the BF—with a radically simple design. Featuring a 24.6 MP full-frame (35mm) sensor, it has just three physical buttons, ...
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Because infected host cells ordinarily lack RNA-dependent RNA polymerase (RdRp) activity, these RNA viruses encode a replicative polymerase essential for the production of progeny. Such virally ...
The Positive Transcription Elongation Factor b (P-TEFb) phosphorylates Ser2 residues of the C-terminal domain (CTD) of the largest subunit (RPB1) of RNA polymerase II and is essential for the ...
Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of ...