Ricky Pearsall leads the San Francisco 49ers in receiving on Monday Night Football, showcasing resilience in a challenging ...

San Francisco 49ers fans were likely collectively holding their breath after starting quarterback Brock Purdy left Monday’s ...

Amid a difficult season marred by injuries, the San Francisco 49ers will stick with their head coach Kyle Shanahan and ...

Who are the 10 greatest San Francisco 49ers of all time? FOX Sports Research compiled the list of Niner greats.

The NFL Week 17 schedule concludes with a Monday Night Football game between the Detroit Lions and San Francisco 49ers at San Francisco's Levi's Stadium. Here's what you need to know before the ...

Few, if any, NFL franchises can match the history, success, and overall talent of the San Francisco 49ers. Tied with the Dallas Cowboys for the third-most Super Bowl wins in NFL history with five ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC ...

Ahead of a massive showdown with the rival Minnesota Vikings to wrap up the regular season, the Detroit Lions flexed their NFC might on Monday night to take down the San Francisco 49ers.

Leonard Floyd is another name to watch out for as he's leading the 49ers with 8.5 sacks on the year. 5. Limiting big plays Despite the injuries San Francisco's offense has dealt with, they are still ...

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Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback ... is meaningless for San Francisco, but he needs ...