The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other ...

At ACS spring meeting, researchers say nitrate metabolizers in the gut may promote α-synuclein aggregation through multistep redox mechanism ...

Enzymes, the core catalysts in life, drive critical biological processes ranging from metabolic regulation to energy ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

Researchers have unveiled the first real look at a mitochondrial protein strongly linked to Parkinson's disease, revealing ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

A comprehensive understanding of these interactions is crucial for unraveling disease mechanisms and guiding the rational ... ESMFold has not yet been tested specifically for protein–peptide docking.

In this valuable study, the authors show the physiological response and molecular pathway mediating the effect of quinofumelin, a developed fungicide with an unknown mechanism ... docking results ...

Department of Chemistry, Israel National Institute of Energy Storage (INIES) and Institute for Nanotechnology & Advanced Materials, Bar-Ilan University, Ramat-Gan 5290002, Israel ...