We are signing off for the day. There are just two sleeps until the spring statement - though it may be trepidation more than excitement keeping you up at night. We'll have more preview coverage ...

Animal experiments are widely used to develop new medicines and to test the safety of other products. Many of these experiments cause pain to the animals involved or reduce their quality of life ...

Sarah Vine and Andrew Pierce bring their own no-holds-barred opinions, insights and reaction (clue is in the title) to the biggest stories of the week. New episodes every Wednesday, wherever you ...