Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair.

Ten projects at Queen’s are receiving support from the Canadian Institutes of Health Research to advance research that will have a high impact on health care knowledge and delivery.

When we think of type 2 diabetes, images of heart problems or kidney damage often come to mind. But lurking quietly behind these well-known complications is another serious threat—bone disease.

A pioneering study offers unprecedented insights into the bone immune microenvironment of type 2 diabetic mice, uncovering a unique genetic profile ...

A new analysis provides substantial evidence that paramagnetic rim lesions drive disability in MS and are targetable with a ...

Neuroimmune modulation represents a promising treatment strategy that uses vagus nerve stimulation to reduce inflammation in RA.

This study is the first to specifically investigate a macrophage subset responsive to the PGE2 and TNF combination in the context of ICI-RA, describes a new and easily reproducible in vitro model, and ...

As GRIB researcher Lilian Marie Boll explains, "We found that in a subset of patients with advanced ... and the abundance of proinflammatory macrophages. Additionally, the researchers identified ...