“The FDA approval of KHINDIVI is a tremendous achievement for Eton and more importantly, a pivotal step forward for pediatric patients with adrenal insufficiency. As a home-grown program, our ...

"Hyperosmolarity induces light scatter that's equivalent to a grade 2 to 3 cataract," Dr. Nijm said. "What that did show in the study is patients could [undergo] a perfect cataract surgery, pick the ...

An important aspect concerning the malignant behavior of GBM is the peculiar versatility to rapidly adapt to changes in metabolic needs, hypoxia, hyperosmolarity and nutrients availability. The high ...

Tear film instability associated with MGD leads to tear hyperosmolarity, resulting in apoptosis and inflammation of the ocular surface. Patients suffering from DED complain of symptoms including ...

Diabetes is a metabolic condition defined by consistently elevated blood glucose levels. Hyperglycemia is characterized by heightened hunger, thirst, and urination. Numerous consequences may arise ...

In hyperosmolarity-induced DED corneal epithelial cells, AST increased the expression of ferritin to promote iron storage and reduce Fe 2+ overload. It increased glutathione (GSH) and GPX4, scavenged ...

Causes Of Excessive Thirst At Night Medically referred to as polydipsia, extreme thirst can have several causes. It is characterised by a dry mouth, an abnormal urge to drink fluids all the time ...

Bausch + Lomb has acquired Trukera Medical in an effort to expand its position in dry eye care, according to a press release. Bausch’s announcement highlighted Trukera’s ScoutPro device, which ...

Commercially-available eye drops can improve the hyperosmolarity of the ocular surface and reduce inflammation in individuals with dry eye disease (DED), according to study published in Cornea.

“Dry eye” is a multifactorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have ...

A novel therapy for dry eye disease (DED) achieved clinically meaningful and statistically significant results in the pivotal Phase III MELODY-1 clinical trial. 1 PL9643 ophthalmic solution, developed ...

Understanding Hyperosmolarity Hyperosmolarity refers to an elevated concentration of solutes in the blood, disrupting the balance of fluids in the body. This imbalance can lead to excessive thirst ...