Retatrutide, a synthetic peptide with unique properties, has recently gained attention for its multifunctional roles and the ...

Objective—Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects on pancreatic β- and α-cells. Previous studies have focused on the improvements in β-cell function ...

Therefore, AMPs could be key determinants in regulating AV development and progression, linking acne-associated immune responses and metabolic factors, like insulin/IGF-1 and PI3K ... including ...

Tirzepatide (Mounjaro, Persovance, Zepbound) is a 39-amino-acid modified peptide based on the GIP sequence ... The drug candidate is a new biological entity (NBE) which acts by targeting glucagon like ...

The formation of HIV-induced CPSF6 puncta is critical for restoring HIV-1 nuclear reverse transcription (RT). CPSF6 protein lacking the ... Figure 4. Sequences of FG and LCRs or substituted amino ...

The global prevalence of MASLD is substantial, with estimates ranging from 30% to 32%, and the incidence of associated conditions like liver fibrosis ... 1RAs in MASLD GLP-1 is a gut-derived ...

Background/Aims Studies in animals suggest a physiological role for glucagon-like peptide-1-(7–36)-amide (GLP-1) in regulating satiety. The role of GLP-1 in regulating food intake in man has, however, ...

This Viewpoint discusses factors associated with the prevalence of obesity worldwide and whether the novel glucagon-like peptide-1 receptor agonists (GLP-1) can help unlock a health systems response ...

People with diabetes who were taking GLP-1 receptor agonist drugs such as tirzepatide and semaglutide had significantly lower ...