HILIC uses a polar stationary phase, such as silica or polar bonded phase, and the mobile phase consists of 5- 40% water that is combined with a less polar solvent, such as acetonitrile. Polar or ...

Peak shape can be affected by the high amount of acetonitrile in the injection solvent. More complex to use than other liquid chromatography techniques. Applications of HILIC in Several Industries.

Ineos shuttered an acrylonitrile complex and an accompanying acetonitrile unit in Seal Sands, England, in 2020. The firm continues to operate plants in Lima, Ohio, and Green Lake, Texas.