TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Resistance is achieved through mutations at position 63 or ...

That process, called carbon fixation, resulted in the assembly of two three-carbon molecules called 3-phosphoglycerate (3-PGA ...

Ancient microbes illustrate a particular kind of respiration in which carbon dioxide and hydrogen are combined to form acetic ...

This time, with the help of Osaka University's cryo-electron microscopy equipment, the scientists revealed at near-atomic resolution the enzymes ... have evolved from ATP synthase," Professor ...

This time, with the help of Osaka University's cryo-electron microscopy equipment, the scientists revealed at near-atomic resolution the enzymes known as ATPases ... mobile are thought to have evolved ...

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including isocitrate dehydrogenase [NAD(+)] 3 catalytic subunit alpha (IDH3A), ATP synthase subunit delta (ATPD), N-ethylmaleimide sensitive factor, vesicle fusing ATPase (NSF), as well as 75 kDa ...

Enzymes, the core catalysts in life, drive critical biological processes ranging from metabolic regulation to energy ...

Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...