By putting a carbon atom in place of a core oxygen, chemists constructed an opioid that blocks pain with less respiratory ...

A major scientific advance in protein modeling developed by Microsoft Research AI for Science, has been published in Science. The study introduces BioEmu, a generative deep learning system that ...

Establishing stimulus-responsive nanosystems for the codelivery of anticancer drug and oligonucleotide is a promising strategy in cancer treatment owing to the combination of chemotherapy and gene ...

Several mathematical and physical models of corona effect have been developed over the world. The main difference between them resides in the modeling techniques and the adopted hypotheses. To the ...

What follows is a review of works related to lignin molecular modeling. Besombes et al. (2003) studied the computational conformational properties of model β-O-4 lignin compounds using molecular ...

This would facilitate the screening of new drugs for the treatment of gout. Using computational methods for homology modeling and molecular dynamics simulations, the structural model of mouse NLRP3 ...

This paper presents an analytical comparison of active and passive receiver models in diffusive molecular communication. In the active model, molecules are absorbed when they collide with the receiver ...

CUDC-907 is a novel, dual-acting small molecule compound designed to simultaneously inhibit the activity of histone deacetylase (HDAC) and phosphatidylinositol 3-kinase (PI3K). Treatment with CUDC-907 ...

Iambic Taps Lambda for Increased AI Compute as it Develops the Next Generation of Enchant, a Breakthrough AI Molecular Property Prediction Model for Drug Discovery ...