Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

SciLifeLab researchers Alexander Mühleip and Alexey Amunts from Stockholm University solved the structure of a mitochondrial ATP synthase with native lipids.

However, before the energy can be used, it is first transformed into a form which the organism can handle easily. This special carrier of energy is the molecule adenosine triphosphate, or ATP. Its ...

Hours after the Professional Tennis Players Association (PTPA) announced a series of lawsuits against the sport’s governing bodies, the ATP has issued an official statement rejecting the ...

But building ATP's complex chemical structure from scratch is energy intensive and requires six separate ATP-driven steps; while convincing models do allow for prebiotic formation of the ATP ...

Andy Roddick takes a swipe at the current leadership structure of the ATP, which has a seven-person board of directors—with three tournament representatives, three players representatives and a ...

Structure-based drug designers identify and optimize small molecules that affect the activity of target proteins, such as kinases, by understanding and modeling 3-D molecular interactions.

In the June issue of Cancer Letters, the research team reported that bullatacin preferentially killed the multidrug-resistant cells by inhibiting the production of adenosine triphosphate, or ATP. ATP ...

ATP synthase is a critical enzyme in the synthesis of ATP for M. tuberculosis. [16, 23] Binding of TMC207 to the oligomeric and proteolipic subunit c of mycobacterial ATP synthase leads to ...

Until recently, it was though that the microbial degradation of aromatic compounds was absolutely dependent on the use of molecular oxygen for ring cleavage. However, as described here by Fuchs ...

Although the genes encoding the components of the ATP synthase operon are downregulated by decreased metabolic and replication requirements, this enzyme still represents a sensitive drug target.