San Francisco is a 6.5-point favorite Sunday. Here are our 49ers vs. Buccaneers predictions and best bets for NFL Week 10. Note: Odds are based on the best value our experts find as of publication; check lines closer to game time to ensure you get the best ...

The 49ers rack up just 0.7 fewer points per game (26.3) than the Buccaneers allow (27.0). San Francisco racks up 412.4 yards per game, 25.7 more yards than the 386.7 yards that Tampa Bay gives up per outing. This year, the 49ers have turned the ball over 11 times, while the Buccaneers have forced 11.

The San Francisco 49ers are fresh off their bye week and heading to Tampa Bay to take on the Buccaneers. They will have some reinforcements, such as running back Christian McCaffrey, who appears set to make his 2024 season debut.

A person familiar with the matter says San Francisco 49ers star defensive end Nick Bosa has been fined by the NFL for wearing a hat with a pro-Donald Trump message during a postgame television interview.

San Francisco 49ers defensive end Nick Bosa has been fined by the NFL for wearing a "Make America Great Again” hat while crashing an interview.

The NFL has fined San Francisco 49ers star Nick Bosa for wearing a MAGA hat while crashing a television interview after a game Oct. 27.

The 49ers activated running back Christian McCaffrey from injured reserve Saturday, setting up his season debut on Sunday vs. the Bucs.

Spending the first half of the season as a spectator while he worked his way back from Achilles tendinitis took its toll on San Francisco 49ers All-Pro running back Christian McCaffrey