The 49ers are riding a tow game losing streak into Week 17. They are poised to increase it to three in their matchup with the Lions. Here are three reasons why the 49ers will lose to the Lions.

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

The Detroit Lions and San Francisco 49ers have released their final injury reports of the week ahead of their Monday night showdown in Week 17 and there are a total of six players ruled out and ...

Charvarius Ward will join the list of 49ers missing Monday night’s game against the Lions at Levi’s Stadium after the team ruled him out Sunday afternoon. The veteran cornerback and his ...

Another San Francisco 49ers starting offensive lineman is missing from practice. Starting right tackle Colton McKivitz did not participate in Friday's session. McKivitz was a limited participant ...

The injury report for the Detroit Lions (13-2) heading into their matchup versus the San Francisco 49ers (6-9) has five players. The 49ers (6-9) currently have 15 players listed on this week's ...

At Levi's Stadium on Monday, Amon-Ra St. Brown and the Detroit Lions face George Kittle and the San Francisco 49ers in a matchup between two excellent pass-catchers, starting at 8:15 p.m. ET.

The San Francisco 49ers are prepping for Week 17 against the Detroit Lions on Monday Night Football. What they're not prepping for is a playoff push in January. At 6-9, Kyle Shanahan and the 49ers ...

There doesn't seem to be any question about quarterback Brock Purdy's future with the San Francisco 49ers. All indicators are the team is happy with his development and that his contract extension ...

San Francisco 49ers offensive tackle Trent Williams is largely considered one of the greatest to ever play the position. With 11 Pro Bowls and four All-Pro teams under his belt, Williams has been ...