Using in-vitro models of a specific type of brain cell, scientists show that neurons are capable of changing from one type to ...

How cardiac cell fates are specified during heart development remains elusive. This study identifies a level-dependent role ...

Sphere Bio's Cyto-Cellect Assay Kit integrates viability and antibody detection, streamlining workflows and ensuring optimal selection of high-producing clones.

The study is published in the journal Cell. When it comes to piecing together the inner ... By mapping these movements into ...

3D cell culture has the potential to provide alternative ways to study organ behavior via the use of organoids and is expected to eventually bridge the gap between 2D cell culture and animal models.

Therapeutic discovery for SCLC has been challenging and the existing pre-clinical models often fail to recapitulate actual tumor pathophysiology. To address this, we developed a bioengineered ...

Its use in cell tracking is limited ... training of deep-learning models. Moreover, annotation, training, prediction, and proofreading currently lack a unified user interface. We present ELEPHANT, an ...

In this study, using molecular profiling and single-cell RNA sequencing (scRNA-seq) of multiple mouse models of breast cancer, we demonstrated that various tumors driven by different oncogenic events ...