The brain has plans in place when fires break out. Normally, a molecule called PKD1 rushes in to the rescue, but in ...

To date, the GeM-HD consortium has studied thousands of people with HD and hundreds of thousands of spelling changes in every ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

We all have days when we feel irritable, like when you’re stuck in traffic, or someone cuts in line at the grocery store. But for people living with Huntington’s disease (HD), irritability isn’t just ...

Spark and Roche issued a joint community letter to share that the first patient has been dosed in a new HD gene therapy trial. To capture your interest with a romance, let’s talk about how these ...

DNA-based drugs called antisense oligonucleotides, or ASOs, are now in multiple clinical trials in Huntington’s disease, aiming to lower production of the harmful mutant huntingtin protein in the ...

This week, we heard an update from Roche about their huntingtin-lowering therapy, tominersen, currently being tested in the GENERATION HD2 trial. An independent data monitoring committee (iDMC) that ...

Researchers have updated the system that classifies Huntington’s disease progression. Tracking progression in 4 stages will make clinical trial screening and data interpretation easier and faster, and ...

There has been a lot of buzz in the Huntington’s disease (HD) space recently with multiple updates from companies testing many different drugs in the clinic. As these drugs move closer to seeking ...