Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

Iridium (Ir) catalysts are essential for the acidic oxygen evolution reaction (OER) in proton-exchange membrane water electrolyzers (PEMWEs), but their high cost, scarcity, and geographical ...

Fluorescence imaging in the shortwave infrared (SWIR) window enables deeper tissue and higher-contrast visualization of pathological events compared to that in the conventional near-infrared (NIR) ...

Major challenges remain to precisely detect low-abundance proteins rapidly and cost-effectively from diverse biofluids. Here, we present a gold nanoparticle (AuNP)-supported, rapid electronic ...

l-Serine, a nonessential amino acid in humans, possesses significant physiological functions and is widely used in the food, cosmetic, and pharmaceutical industries. Driven by steadily growing market ...

Antimicrobial peptides (AMPs) are promising alternatives to traditional antibiotics. This study uses alchemical free energy simulations to design ultrashort, cationic, broad-spectrum membrane-active ...

The asymmetric hydrogenation of substituted benzenes with oxazoline imino (pyridine) (OIP) molybdenum precatalysts is described. A comparison of the hydrogenation activities between alkylbenzenes and ...

Permethrin, a commonly used type I pyrethroid insecticide, has been shown to induce insulin resistance and adipogenesis, however the molecular mechanisms driving these effects remain unclear. This ...

A Novel PSMA/FAP-Specific Radiotracer 99mTc-HFaPSMA for Diagnosis of PSMA-Negative Prostate Cancer: From Preclinical Validation to Clinical Translation ...

We report herein an Fe-catalyzed asymmetric reductive cross-coupling of carbonyl-containing ketimines with unactivated alkyl halides, enabling the efficient synthesis of enantioenriched α-tertiary ...

Au nanoclusters (NCs), with discrete electronic structures and tunable properties, are promising building blocks for nanoelectronics. However, maximizing their potential requires a deeper ...

Layered materials have emerged as a promising platform for the rational design of high-performance electrodes in rechargeable magnesium ion batteries (RMBs). The presence of weakly bonded van der ...