Crew-10 astronauts will board SpaceX Falcon 9 rocket to International Space Station, which sets up the return to Earth of Butch Wilmore, Suni Williams

Reaching orbit from NASA’s Kennedy Space Center, the newest crew includes NASA’s Anne McClain and Nichole Ayers, both military pilots; and Japan’s Takuya Onishi and Russia’s Kirill Peskov, both former airline pilots. They will spend the next six months at the space station, considered the normal stint, after springing Wilmore and Williams free.

NASA astronauts Sunita Williams, Nick Hague, Barry Wilmore, and Donald Pettit unbox Thanksgiving meals, from the International Space Station (ISS), in this screen grab taken from a handout video, released on November 26,

The four newcomers — representing the U.S., Japan and Russia — will spend the next few days learning the station's ins and outs.

SpaceX delivered a four-person crew to the International Space Station early Sunday, setting the stage for Barry Wilmore and Sunita Williams to depart.