Objective—Glucagon-like peptide 1 (GLP-1) exerts beneficial antidiabetic actions via effects on pancreatic β- and α-cells. Previous studies have focused on the improvements in β-cell function ...

Because of side chain interactions, the sequence and location of amino acids in a particular protein guides where the bends and folds occur in that protein (Figure 1). The final shape adopted by a ...

The glucagon-like peptides (GLP-1 and GLP-2) are processed from the proglucagon polypeptide and secreted in equimolar amounts but have opposite effects on chylomicron (CM) production, with GLP-1 ...

Retatrutide, a synthetic peptide with unique properties, has recently gained attention for its multifunctional roles and the ...

Retatrutide is a synthetic peptide, which research indicates functions as a triple agonist for type 2 diabetes and weight loss. Peptides, small chains of amino acids, have been hypothesized to ...

The sequence of amino acids in the chain determines ... The shape of a protein determines what it can interact with, just like the shape of a key determines which locks it can operate.