To date, experts consider most cases of ALS to be “sporadic,” with the only two established risk factors including age ... The most common cause of ALS-related death is respiratory failure ...

Although a small percentage of patients with ALS have a familial form, most have sporadic disease. Many risk factors for the development of sporadic ALS have been proposed and examined ...

This important study demonstrates that physical activity is not a risk factor for the development of ALS and may actually ... of exposures may have been the cause; this study eliminates physical ...

Mitochondrial genome mutations may be linked to ALS, per a study, opening the door for new ways to diagnosing and treating ...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which neurons in the central nervous system that help ...

The pathway leading to the telltale sign of ALS, protein aggregation in the cytoplasm of motor neurons, has been revealed.

Altered activity of ancient viral genes were linked to neurodegenerative diseases including ALS in a recent analysis.

Thirteen of the mutations increased the risk of ALS, while 38 were protective ... whereas nuclear DNA is inherited from both ...

Trace Neuroscience launched on Tuesday to announce that it is developing a genetic treatment targeting UNC13A, a gene linked ...

There are currently no FDA-approved treatments for ALS that preserve breathing function or extend life by more than two or three months, the company noted. The leading cause of death in patients ...

He stressed the importance of the molecular-level research saying that "knowing the molecular cause and targeting ... population at a greater risk of developing ALS". Furthermore, "we have made ...

Thirteen of the mutations increased the risk of ALS, while 38 were protective ... whereas nuclear DNA is inherited from both parents. Hereditary genetic factors are the main cause of ALS cases – only ...