Although a small percentage of patients with ALS have a familial form, most have sporadic disease. Many risk factors for the development of sporadic ALS have been proposed and examined ...

This important study demonstrates that physical activity is not a risk factor for the development of ALS and may actually ... of exposures may have been the cause; this study eliminates physical ...

"If the root causes are different for all these ... variants are believed to account for about 50% of ALS risk (with environmental factors making up the rest), most of the variants that contribute ...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which neurons in the central nervous system that help ...

Altered activity of ancient viral genes were linked to neurodegenerative diseases including ALS in a recent analysis.

Thirteen of the mutations increased the risk of ALS, while 38 were protective ... whereas nuclear DNA is inherited from both ...

There are currently no FDA-approved treatments for ALS that preserve breathing function or extend life by more than two or three months, the company noted. The leading cause of death in patients ...

They govern voluntary movements and muscle control. ALS causes these motor neurons to degenerate over time until they eventually die. The disease is progressive, meaning the symptoms get worse over ...

Amyotrophic lateral sclerosis causes motor neurons in the brain to degenerate, taking away the ability to move, talk and breathe, while generally leaving intellect and memory intact. Addressing ...

As an indication of the severity of ALS ... [cause of a disease] of Cushing's syndrome often experienced a less rapid decline, but their health outcomes are poor and include a significantly higher ...

Biogen’s treatment is the first approved treatment to target a genetic cause of ALS. “For more than a decade, Biogen has been steadfast in our commitment to pursuing treatments for ALS ...

The mutations were mapped by a group at the Federal University of São Paulo and collaborators in an analysis of mitochondrial genomes. Thirteen increase the risk of ALS and 38 are protective.