A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ...

ATP works by losing the endmost phosphate group when instructed to do so by an enzyme. This reaction releases a lot of energy, which the organism can then use to build proteins, contact muscles, etc.

TMC207 is a first-in-class anti-TB diarylquinoline (also named R207910 or the 'J' compound) with activity ... the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis ...

Understanding how the energy-carrying molecule in cells does its job may have major implications for combating cancer and type 2 diabetes, among other diseases.

The work is published in the journal Structure. Proteins must move ... For activation, an inactive form of ATP—a so-called caged compound—was used, which releases ATP when the laser hits ...

How do cells meet our bodies’ ever changing energy needs? In most animal cells, adenosine triphosphate (ATP), a compound with high potential energy, works as the main carrier of chemical energy.